MolNFT v1 · #92405 · protein
Crystal structure of a glutamyl-tRNA synthetase glurs from burkholderia thailandensis bound to L-glutamate
4G6Z · Glutamate-tRNA ligase: “Crystal structure of a glutamyl-tRNA synthetase glurs from burkholderia thailandensis bound to L-glutamate”. X-ray diffraction, 3 ligands (GLU, NA, CL), 1 pocket (best druggability 0.68). MolNFT v1 #92405 on…
- PDB
- 4G6Z
- Type
- protein
- Length
- 380 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamate-tRNA ligase
- EC
- 6.1.1.17
- UniProt
- Q2SX36
- Ligands
- GLU, NA, CL
- Pockets
- 1 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate-tRNA ligase (EC 6.1.1.17) | protein | 380 | 45% helix, 15% strand | Q2SX36 |
Ligands and binding sites
- GLU · Glutamic acid · ligand · chains A
- NA · Sodium ion · metal · chains A
- CL · Chloride ion · ion · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 344 | 0.68 | 0.82 | 44 | GLU |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 4G6Z · Crystal structure of a glutamyl-tRNA synthetase GluRS from Burkholderia thailandensis… · the same entry in another collection · chain A against A, TM-score 1.00
- Q2SX36 · AlphaFold monomer V2.0 prediction for glutamate--tRNA ligase (Q2SX36) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2SX36
- Elsewhere: RCSB PDB 4G6Z · PDBe 4G6Z · UniProt Q2SX36
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