MolNFT v1 · #92283 · protein

Crystal structure of streptomyces sp. SF2575 glycosyltransferase SSFS6, complexed with thymidine diphosphate

4G2T: “Crystal structure of streptomyces sp. SF2575 glycosyltransferase SSFS6, complexed with thymidine diphosphate”. X-ray diffraction, 1 ligand (TYD), 4 pockets (best druggability 0.78). MolNFT v1 #92283 on GenesisL1: 3D structure…

PDB: 4G2T
Type: protein
Length: 356 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SSFS6
UniProt: D6MSX4
Ligands: TYD
Pockets: 4 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SSFS6	protein	356	45% helix, 17% strand	D6MSX4

Ligands and binding sites

TYD · Thymidine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	209	0.78	0.93	38	TYD
2	181	0.48	0.76	28	empty
3	67	0.30	0.74	15	empty
4	51	0.29	0.76	12	empty

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

4G2T · Crystal Structure of Streptomyces sp. SF2575 glycosyltransferase SsfS6, complexed with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D6MSX4
Elsewhere: RCSB PDB 4G2T · PDBe 4G2T · UniProt D6MSX4

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