MolNFT v1 · #92183 · protein

Crystal structure of HP0197-G5

4FZQ · Uncharacterized protein conserved in bacteria: “Crystal structure of HP0197-G5”. X-ray diffraction, 4 pockets (best druggability 0.41). MolNFT v1 #92183 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4FZQ
Type: protein
Length: 464 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein conserved in bacteria
UniProt: A4VZ16
Pockets: 4 · best druggability 0.41

Structure

x-ray diffraction · 3 distinct chains · 0% helix, 67% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	Uncharacterized protein conserved in bacteria	protein	79	0% helix, 59% strand	A4VZ16
B	Uncharacterized protein conserved in bacteria	protein	78	0% helix, 76% strand	A4VZ16
D, E, F	Uncharacterized protein conserved in bacteria	protein	76	0% helix, 67% strand	A4VZ16

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	143	0.41	0.74	23	empty
2	141	0.38	0.73	26	empty
3	65	0.28	0.72	15	empty
4	55	0.27	0.74	16	empty

Interfaces

8 interfaces between chains.

D–E · 480 Å² buried · 8 hydrogen bonds · protein-protein
A–B · 384 Å² buried · 11 hydrogen bonds · protein-protein
A–D · 301 Å² buried · 5 hydrogen bonds · protein-protein
C–D · 298 Å² buried · 7 hydrogen bonds · protein-protein
B–E · 297 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4FZQ · Crystal structure of HP0197-G5 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4VZ16
Elsewhere: RCSB PDB 4FZQ · PDBe 4FZQ · UniProt A4VZ16

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