MolNFT v1 · #92027 · protein

Crystal structure of a leucine aminopeptidase precursor (BT_2548) from bacteroides thetaiotaomicron vpi-5482 at 1.30 a resolution

4FUU: “Crystal structure of a leucine aminopeptidase precursor (BT_2548) from bacteroides thetaiotaomicron vpi-5482…”. X-ray diffraction, 3 ligands (UNL, ZN, PO4), 1 pocket (best druggability 0.46). MolNFT v1 #92027 on GenesisL1: 3D…

PDB: 4FUU
Type: protein
Length: 290 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Leucine aminopeptidase
UniProt: Q8A4P9
Ligands: UNL, ZN, PO4
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Leucine aminopeptidase	protein	290	38% helix, 19% strand	Q8A4P9

Ligands and binding sites

UNL · Unknown ligand · ligand · chains A
ZN · Zinc ion · metal · chains A
PO4 · Phosphate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	109	0.46	0.79	20	UNL

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

4FUU · Crystal structure of a leucine aminopeptidase precursor (BT_2548) from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8A4P9
Elsewhere: RCSB PDB 4FUU · PDBe 4FUU · UniProt Q8A4P9

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