MolNFT v1 · #91945 · protein
Crystal structure of bacillus thuringiensis plcr in its apo form
4FSC · Transcriptional activator plcr protein: “Crystal structure of bacillus thuringiensis plcr in its apo form”. X-ray diffraction, 14 pockets (best druggability 0.81). MolNFT v1 #91945 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4FSC
- Type
- protein
- Length
- 1,058 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional activator plcr protein
- UniProt
- Q45782
- Pockets
- 14 · best druggability 0.81
Structure
x-ray diffraction · 3 distinct chains · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional activator plcr protein | protein | 264 | 69% helix, 0% strand | Q45782 |
| B, D | Transcriptional activator plcr protein | protein | 264 | 70% helix, 0% strand | Q45782 |
| C | Transcriptional activator plcr protein | protein | 266 | 68% helix, 0% strand | Q45782 |
Pockets
14 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 815 | 0.81 | 0.83 | 93 | empty |
| 2 | 386 | 0.74 | 0.84 | 56 | empty |
| 3 | 595 | 0.71 | 0.78 | 64 | empty |
| 4 | 533 | 0.70 | 0.79 | 65 | empty |
| 5 | 267 | 0.68 | 0.83 | 29 | empty |
Interfaces
4 interfaces between chains.
- A–D · 1760 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 1753 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 188 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 186 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4FSC · Crystal Structure of Bacillus thuringiensis PlcR in its apo form · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q45782
- Elsewhere: RCSB PDB 4FSC · PDBe 4FSC · UniProt Q45782
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.