MolNFT v1 · #9183 · protein
Crystal structure of pyridoxine 5'-phosphate synthase
1HO1: “Crystal structure of pyridoxine 5'-phosphate synthase”. X-ray diffraction, 9 pockets (best druggability 0.53). MolNFT v1 #9183 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1HO1
- Type
- protein
- Length
- 954 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pyridoxine 5'-phosphate synthase
- UniProt
- P0A794
- Pockets
- 9 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pyridoxine 5'-phosphate synthase | protein | 235 | 49% helix, 17% strand | P0A794 |
| C, D | Pyridoxine 5'-phosphate synthase | protein | 242 | 48% helix, 17% strand | P0A794 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 163 | 0.53 | 0.79 | 27 | empty |
| 2 | 172 | 0.53 | 0.79 | 23 | empty |
| 3 | 171 | 0.52 | 0.79 | 25 | empty |
| 4 | 167 | 0.52 | 0.79 | 25 | empty |
| 5 | 167 | 0.44 | 0.74 | 22 | empty |
Interfaces
2 interfaces between chains.
- A–C · 585 Ų buried · 12 hydrogen bonds · protein-protein
- B–D · 575 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A794
- Elsewhere: RCSB PDB 1HO1 · PDBe 1HO1 · UniProt P0A794
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