MolNFT v1 · #91567 · protein
Crystal structures of the CID1 poly (U) polymerase reveal the mechanism for UTP selectivity
4FH3 · POLY(A) RNA polymerase protein CID1: “Crystal structures of the CID1 poly (U) polymerase reveal the mechanism for UTP selectivity”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #91567 on GenesisL1: 3D structure…
- PDB
- 4FH3
- Type
- protein
- Length
- 323 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- POLY(A) RNA polymerase protein CID1
- EC
- 2.7.7.-
- UniProt
- O13833
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(A) RNA polymerase protein CID1 (EC 2.7.7.-) | protein | 323 | 46% helix, 14% strand | O13833 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 688 | 0.67 | 0.75 | 53 | empty |
| 2 | 65 | 0.32 | 0.75 | 13 | empty |
Compared structures
- 4FH3 · Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP… · the same entry in another collection · chain A against A, TM-score 1.00
- O13833 · AlphaFold monomer V2.0 prediction for terminal uridylyltransferase CID1 (O13833) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O13833
- Elsewhere: RCSB PDB 4FH3 · PDBe 4FH3 · UniProt O13833
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