MolNFT v1 · #91539 · protein
Crystal structure of human CALCIUM/CALMODULIN-dependent protein kinase I apo form
4FGB · CALCIUM/CALMODULIN-dependent protein kinase type 1: “Crystal structure of human CALCIUM/CALMODULIN-dependent protein kinase I apo form”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #91539 on GenesisL1: 3D…
- PDB
- 4FGB
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CALCIUM/CALMODULIN-dependent protein kinase type 1
- EC
- 2.7.11.17
- UniProt
- Q14012
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CALCIUM/CALMODULIN-dependent protein kinase type 1 (EC 2.7.11.17) | protein | 282 | 42% helix, 17% strand | Q14012 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.53 | 0.79 | 28 | empty |
| 2 | 55 | 0.39 | 0.81 | 18 | empty |
Compared structures
- 4FGB · Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form · the same entry in another collection · chain A against A, TM-score 1.00
- Q14012 · AlphaFold monomer V2.0 prediction for CALCIUM/CALMODULIN-dependent protein kinase type 1… · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14012
- Elsewhere: RCSB PDB 4FGB · PDBe 4FGB · UniProt Q14012
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