MolNFT v1 · #91509 · protein
The structure of cowpox virus CPXV018 (omcp)
4FFE · CPXV018 protein: “The structure of cowpox virus CPXV018 (omcp)”. X-ray diffraction, 4 pockets (best druggability 0.78). MolNFT v1 #91509 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4FFE
- Type
- protein
- Length
- 450 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CPXV018 protein
- UniProt
- Q8QN43
- Pockets
- 4 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X, Y, Z | CPXV018 protein | protein | 150 | 32% helix, 37% strand | Q8QN43 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1102 | 0.78 | 0.80 | 109 | empty |
| 2 | 60 | 0.31 | 0.76 | 16 | empty |
| 3 | 59 | 0.29 | 0.75 | 13 | empty |
| 4 | 57 | 0.26 | 0.73 | 12 | empty |
Interfaces
3 interfaces between chains.
- X–Z · 580 Ų buried · 3 hydrogen bonds · protein-protein
- X–Y · 570 Ų buried · 2 hydrogen bonds · protein-protein
- Y–Z · 555 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 4FFE · The structure of cowpox virus CPXV018 (OMCP) · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8QN43
- Elsewhere: RCSB PDB 4FFE · PDBe 4FFE · UniProt Q8QN43
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