MolNFT v1 · #91460 · protein
Eutl from clostridium perfringens, crystallized under reducing conditions
4FDZ · Ethanolamine utilization protein: “Eutl from clostridium perfringens, crystallized under reducing conditions”. X-ray diffraction, 1 ligand (NA), 6 pockets (best druggability 0.52). MolNFT v1 #91460 on GenesisL1: 3D structure…
- PDB
- 4FDZ
- Type
- protein
- Length
- 663 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ethanolamine utilization protein
- UniProt
- Q8XLZ0
- Ligands
- NA
- Pockets
- 6 · best druggability 0.52
Structure
x-ray diffraction · 3 distinct chains · 36% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ethanolamine utilization protein | protein | 217 | 35% helix, 28% strand | Q8XLZ0 |
| B | Ethanolamine utilization protein | protein | 221 | 35% helix, 26% strand | Q8XLZ0 |
| C | Ethanolamine utilization protein | protein | 225 | 38% helix, 27% strand | Q8XLZ0 |
Ligands and binding sites
- NA · Sodium ion · metal · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.52 | 0.80 | 22 | empty |
| 2 | 139 | 0.51 | 0.79 | 24 | empty |
| 3 | 130 | 0.49 | 0.79 | 23 | empty |
| 4 | 127 | 0.49 | 0.79 | 23 | empty |
| 5 | 121 | 0.49 | 0.80 | 23 | empty |
Interfaces
3 interfaces between chains.
- A–C · 1647 Ų buried · 19 hydrogen bonds · protein-protein
- B–C · 1627 Ų buried · 21 hydrogen bonds · protein-protein
- A–B · 1540 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 4FDZ · EutL from Clostridium perfringens, Crystallized Under Reducing Conditions · the same entry in another collection · chain A against A, TM-score 1.00
- Q8XLZ0 · AlphaFold monomer V2.0 prediction for bacterial microcompartment shell protein eutl… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8XLZ0
- Elsewhere: RCSB PDB 4FDZ · PDBe 4FDZ · UniProt Q8XLZ0
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