MolNFT v1 · #91437 · protein

Crystal structure of the third beta-gamma-crystallin domain of CRYBG3 (betagamma-crystallin domain-containing protein 3) from mus musculus

4FD9 · BETA/GAMMA crystallin domain-containing protein 3: “Crystal structure of the third beta-gamma-crystallin domain of CRYBG3 (betagamma-crystallin domain-containing…”. X-ray diffraction, 1 pocket (best druggability 0.56). MolNFT v1…

PDB: 4FD9
Type: protein
Length: 184 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BETA/GAMMA crystallin domain-containing protein 3
UniProt: Q80W49
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	BETA/GAMMA crystallin domain-containing protein 3	protein	92	12% helix, 45% strand	Q80W49

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	217	0.56	0.78	35	empty

Interfaces

1 interface between chains.

A–B · 756 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

4FD9 · Crystal structure of the third beta-gamma-crystallin domain of Crybg3… · the same entry in another collection · chain A against A, TM-score 1.00
Q80W49 · AlphaFold monomer V2.0 prediction for BETA/GAMMA crystallin domain- containing protein 3… · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q80W49
Elsewhere: RCSB PDB 4FD9 · PDBe 4FD9 · UniProt Q80W49

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