MolNFT v1 · #91402 · protein

Crystal structure of transcription regulator protein RTR1 from kluyveromyces lactis

4FC8 · Transcription protein RTR1: “Crystal structure of transcription regulator protein RTR1 from kluyveromyces lactis”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.49). MolNFT v1 #91402 on GenesisL1: 3D structure…

PDB: 4FC8
Type: protein
Length: 272 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription protein RTR1
UniProt: Q6CK86
Ligands: ZN
Pockets: 2 · best druggability 0.49

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription protein RTR1	protein	133	51% helix, 2% strand	Q6CK86
B	Transcription protein RTR1	protein	139	50% helix, 1% strand	Q6CK86

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	202	0.49	0.76	29	empty
2	77	0.40	0.78	17	empty

Interfaces

1 interface between chains.

A–B · 474 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

4FC8 · Crystal structure of transcription regulator protein Rtr1 from Kluyveromyces lactis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6CK86
Elsewhere: RCSB PDB 4FC8 · PDBe 4FC8 · UniProt Q6CK86

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.