MolNFT v1 · #91338 · protein
Substrate CA/P2 in complex with a human immunodeficiency virus type 1 protease variant
4FAF · HIV-1 protease: “Substrate CA/P2 in complex with a human immunodeficiency virus type 1 protease variant”. X-ray diffraction. MolNFT v1 #91338 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4FAF
- Type
- protein
- Length
- 205 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HIV-1 protease; Substrate CA/P2 peptide
- EC
- 3.4.23.16
- UniProt
- Q000H7
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | HIV-1 protease (EC 3.4.23.16) | protein | 99 | 7% helix, 55% strand | Q000H7 |
| D | Substrate CA/P2 peptide | protein | 7 | 0% helix, 43% strand | — |
Interfaces
3 interfaces between chains.
- A–B · 1846 Ų buried · 39 hydrogen bonds · protein-protein
- B–D · 595 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 435 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 4FAF · Substrate CA/p2 in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q000H7
- Elsewhere: RCSB PDB 4FAF · PDBe 4FAF · UniProt Q000H7
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