MolNFT v1 · #91337 · protein
Substrate P2/NC in complex with a human immunodeficiency virus type 1 protease variant
4FAE · HIV-1 protease: “Substrate P2/NC in complex with a human immunodeficiency virus type 1 protease variant”. X-ray diffraction. MolNFT v1 #91337 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4FAE
- Type
- protein
- Length
- 205 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HIV-1 protease; Substrate P2/NC peptide
- EC
- 3.4.23.16
- UniProt
- Q000H7, Q9YP46
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | HIV-1 protease (EC 3.4.23.16) | protein | 99 | 7% helix, 53% strand | Q000H7 |
| D | Substrate P2/NC peptide | protein | 7 | 0% helix, 43% strand | Q9YP46 |
Interfaces
3 interfaces between chains.
- A–B · 1849 Ų buried · 33 hydrogen bonds · protein-protein
- A–D · 514 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 481 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 4FAE · Substrate p2/NC in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q000H7
- Every structure of UniProt Q9YP46
- Elsewhere: RCSB PDB 4FAE · PDBe 4FAE · UniProt Q000H7 · UniProt Q9YP46
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