MolNFT v1 · #91318 · protein

Ribosomal protein L1 from thermus thermophilus with substitution THR217ALA

4F9T · 50S ribosomal protein L1: “Ribosomal protein L1 from thermus thermophilus with substitution THR217ALA”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.73). MolNFT v1 #91318 on GenesisL1: 3D structure, binding sites…

PDB: 4F9T
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 50S ribosomal protein L1
UniProt: P27150
Ligands: SO4
Pockets: 1 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	50S ribosomal protein L1	protein	226	34% helix, 21% strand	P27150

Ligands and binding sites

SO4 · Sulfate ion · ion · 10 copies · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 3 copies · chains A
MRD · (4R)-2-methylpentane-2,4-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	388	0.73	0.84	55	MPD

Compared structures

4F9T · Ribosomal protein L1 from Thermus thermophilus with substitution Thr217Ala · the same entry in another collection · chain A against A, TM-score 1.00
P27150 · AlphaFold monomer V2.0 prediction for 50S ribosomal protein L1 (P27150) · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27150
Elsewhere: RCSB PDB 4F9T · PDBe 4F9T · UniProt P27150

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