MolNFT v1 · #91299 · protein
Crystal structure of human inosine triphosphate pyrophosphatase P32T variant
4F95: “Crystal structure of human inosine triphosphate pyrophosphatase P32T variant”. X-ray diffraction, 2 pockets (best druggability 0.64). MolNFT v1 #91299 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4F95
- Type
- protein
- Length
- 189 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inosine triphosphate pyrophosphatase
- EC
- 3.6.1.19
- UniProt
- Q9BY32
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inosine triphosphate pyrophosphatase (EC 3.6.1.19) | protein | 189 | 35% helix, 25% strand | Q9BY32 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 494 | 0.64 | 0.76 | 47 | empty |
| 2 | 114 | 0.51 | 0.81 | 28 | empty |
Compared structures
- 4F95 · Crystal structure of human inosine triphosphate pyrophosphatase P32T variant · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BY32 · AlphaFold monomer V2.0 prediction for inosine triphosphate pyrophosphatase (Q9BY32) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BY32
- Elsewhere: RCSB PDB 4F95 · PDBe 4F95 · UniProt Q9BY32
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