MolNFT v1 · #91236 · protein
Crystal structure of the active HIV-1 protease in complex with the products of P1-P6 substrate
4F76: “Crystal structure of the active HIV-1 protease in complex with the products of P1-P6 substrate”. X-ray diffraction. MolNFT v1 #91236 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4F76
- Type
- protein
- Length
- 204 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protease; N terminal product of substrate P1-P6; C terminal product of substrate P1-P6
- EC
- 3.4.23.16
- UniProt
- P03369
Structure
x-ray diffraction · 3 distinct chains · 4% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Protease (EC 3.4.23.16) | protein | 99 | 4% helix, 55% strand | P03369 |
| C | N terminal product of substrate P1-P6 | protein | 3 | 0% helix, 33% strand | — |
| D | C terminal product of substrate P1-P6 | protein | 3 | 0% helix, 0% strand | — |
Interfaces
6 interfaces between chains.
- A–B · 1846 Ų buried · 41 hydrogen bonds · protein-protein
- B–D · 284 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 276 Ų buried · 10 hydrogen bonds · protein-protein
- B–C · 212 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 180 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4F76 · Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03369
- Elsewhere: RCSB PDB 4F76 · PDBe 4F76 · UniProt P03369
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.