MolNFT v1 · #90978 · protein
Crystal structure of the substrate binding domain of E.COLI dnak in complex with pr-bombesin in space group I222
4EZU · Chaperone protein dnak: “Crystal structure of the substrate binding domain of E.COLI dnak in complex with pr-bombesin in space group…”. X-ray diffraction, 3 pockets (best druggability 0.52). MolNFT v1 #90978 on GenesisL1: 3D…
- PDB
- 4EZU
- Type
- protein
- Length
- 229 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chaperone protein dnak; Proline rich bombesin-related protein
- UniProt
- P0A6Y8, Q8QFP2
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chaperone protein dnak | protein | 216 | 42% helix, 27% strand | P0A6Y8 |
| B | Proline rich bombesin-related protein | protein | 13 | 0% helix, 15% strand | Q8QFP2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.52 | 0.82 | 20 | empty |
| 2 | 53 | 0.31 | 0.77 | 13 | empty |
| 3 | 54 | 0.30 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 837 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 4EZU · Crystal structure of the substrate binding domain of E.coli DnaK in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A6Y8 · AlphaFold monomer V2.0 prediction for chaperone protein dnak (P0A6Y8) · a predicted model of the same protein · chain A against A, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A6Y8
- Every structure of UniProt Q8QFP2
- Elsewhere: RCSB PDB 4EZU · PDBe 4EZU · UniProt P0A6Y8 · UniProt Q8QFP2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.