MolNFT v1 · #90757 · protein

Crystal structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, northeast structural genomics consortium (nesg) target OR187

4ESS: “Crystal structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, northeast structural…”. X-ray diffraction, 2 pockets (best druggability 0.65). MolNFT v1 #90757 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 4ESS
Type: protein
Length: 158 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: OR187
Pockets: 2 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	OR187	protein	158	41% helix, 23% strand	—

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	120	0.65	0.88	26	empty
2	79	0.35	0.76	27	empty

Compared structures

4ESS · Crystal Structure of E6D/L155R variant of de novo designed serine hydrolase OSH55… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4ESS · PDBe 4ESS

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