MolNFT v1 · #90739 · protein

Crystal structure of protein hc from homo sapiens at 2 ångström

4ES7 · Protein ambp: “Crystal structure of protein hc from homo sapiens at 2 ångström”. X-ray diffraction, 1 pocket (best druggability 0.71). MolNFT v1 #90739 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4ES7
Type: protein
Length: 166 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein ambp
UniProt: P02760
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein ambp	protein	166	16% helix, 46% strand	P02760

Ligands and binding sites

PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	444	0.71	0.81	38	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4ES7 · crystal structure of protein HC from Homo sapiens at 2 angstrom · the same entry in another collection · chain A against A, TM-score 1.00
P02760 · AlphaFold monomer V2.0 prediction for protein ambp (P02760) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02760
Elsewhere: RCSB PDB 4ES7 · PDBe 4ES7 · UniProt P02760

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