MolNFT v1 · #90733 · protein

Double-stranded endonuclease activity in B. halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated CAS2 protein

4ES1 · BH0342 protein: “Double-stranded endonuclease activity in B. halodurans clustered regularly interspaced short palindromic…”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #90733 on GenesisL1: 3D structure, binding…

PDB: 4ES1
Type: protein
Length: 95 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BH0342 protein
EC: 3.1.-.-
UniProt: Q9KFX8
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BH0342 protein (EC 3.1.-.-)	protein	95	31% helix, 27% strand	Q9KFX8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.29	0.75	13	empty

Compared structures

4ES1 · Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced… · the same entry in another collection · chain A against A, TM-score 1.00
Q9KFX8 · AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS2 (Q9KFX8) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KFX8
Elsewhere: RCSB PDB 4ES1 · PDBe 4ES1 · UniProt Q9KFX8

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