MolNFT v1 · #90727 · protein
Crystal structure of human ryanodine receptor 3 (2597-2800)
4ERV: “Crystal structure of human ryanodine receptor 3 (2597-2800)”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.51). MolNFT v1 #90727 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4ERV
- Type
- protein
- Length
- 194 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ryanodine receptor 3
- UniProt
- Q15413
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ryanodine receptor 3 | protein | 194 | 57% helix, 6% strand | Q15413 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.51 | 0.79 | 16 | empty |
| 2 | 117 | 0.39 | 0.75 | 20 | empty |
| 3 | 65 | 0.36 | 0.78 | 15 | empty |
Compared structures
- 4ERV · Crystal structure of human ryanodine receptor 3 (2597-2800) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15413
- Elsewhere: RCSB PDB 4ERV · PDBe 4ERV · UniProt Q15413
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