MolNFT v1 · #9043 · protein

Melanoma inhibitory activity (mia) protein

1HJD · Human melanoma inhibitory activity protein: “Melanoma inhibitory activity (mia) protein”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #9043 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1HJD
Type: protein
Length: 101 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Human melanoma inhibitory activity protein
UniProt: Q16674
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 0% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Human melanoma inhibitory activity protein	protein	101	0% helix, 39% strand	Q16674

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.32	0.75	15	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1HJD · Melanoma inhibitory activity (MIA) protein · the same entry in another collection · chain A against A, TM-score 1.00
Q16674 · AlphaFold monomer V2.0 prediction for melanoma-derived growth regulatory protein (Q16674) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16674
Elsewhere: RCSB PDB 1HJD · PDBe 1HJD · UniProt Q16674

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