MolNFT v1 · #90187 · protein
Crystal structure of the ectodomain of a receptor like kinase
4EBZ · Chitin elicitor receptor kinase 1: “Crystal structure of the ectodomain of a receptor like kinase”. X-ray diffraction, 3 ligands (NAG, BMA, MAN), 2 pockets (best druggability 0.51). MolNFT v1 #90187 on GenesisL1: 3D structure…
- PDB
- 4EBZ
- Type
- protein
- Length
- 200 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chitin elicitor receptor kinase 1
- UniProt
- A8R7E6
- Ligands
- NAG, BMA, MAN
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chitin elicitor receptor kinase 1 | protein | 200 | 22% helix, 21% strand | A8R7E6 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains A
- BMA · beta-D-mannopyranose · sugar · 2 copies
- MAN · alpha-D-mannopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.51 | 0.77 | 28 | empty |
| 2 | 83 | 0.32 | 0.73 | 17 | empty |
Modifications
Observed in the structure: 4 glycan, 3 disulfide (N-glycosylation, disulfide).
Compared structures
- 4EBZ · Crystal structure of the ectodomain of a receptor like kinase · the same entry in another collection · chain A against A, TM-score 1.00
- A8R7E6 · AlphaFold monomer V2.0 prediction for chitin elicitor receptor kinase 1 (A8R7E6) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8R7E6
- Elsewhere: RCSB PDB 4EBZ · PDBe 4EBZ · UniProt A8R7E6
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