MolNFT v1 · #90015 · protein
Crystal structure of the hat domain of K. lactis RNA14
4E6H · MRNA 3'-end-processing protein RNA14: “Crystal structure of the hat domain of K. lactis RNA14”. X-ray diffraction, 5 pockets (best druggability 0.51). MolNFT v1 #90015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4E6H
- Type
- protein
- Length
- 553 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MRNA 3'-end-processing protein RNA14
- UniProt
- Q6CII8
- Pockets
- 5 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA 3'-end-processing protein RNA14 | protein | 553 | 71% helix, 0% strand | Q6CII8 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.51 | 0.79 | 18 | empty |
| 2 | 161 | 0.49 | 0.78 | 27 | empty |
| 3 | 192 | 0.48 | 0.76 | 24 | empty |
| 4 | 65 | 0.34 | 0.76 | 20 | empty |
| 5 | 53 | 0.30 | 0.75 | 10 | empty |
Compared structures
- 4E6H · CRYSTAL STRUCTURE OF THE HAT domain of k. lactis RNA14 · the same entry in another collection · chain A against A, TM-score 1.00
- Q6CII8 · AlphaFold monomer V2.0 prediction for mRNA 3'-end-processing protein RNA14 (Q6CII8) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6CII8
- Elsewhere: RCSB PDB 4E6H · PDBe 4E6H · UniProt Q6CII8
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