MolNFT v1 · #90013 · protein

Crystal structure of a putative cell division protein ftsz (TFU_1113) from thermobifida fusca yx-ER1 at 2.22 a resolution (psi community target, van wezel G.P.)

4E6E: “Crystal structure of a putative cell division protein ftsz (TFU_1113) from thermobifida fusca yx-ER1 at 2.22…”. X-ray diffraction, 3 ligands (MG, CL, SO4), 3 pockets (best druggability 0.50). MolNFT v1 #90013 on GenesisL1: 3D…

PDB: 4E6E
Type: protein
Length: 306 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cell division protein ftsz
UniProt: Q47QW6
Ligands: MG, CL, SO4
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cell division protein ftsz	protein	306	42% helix, 25% strand	Q47QW6

Ligands and binding sites

MG · Magnesium ion · metal · 4 copies · chains A
CL · Chloride ion · ion · 2 copies · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	173	0.50	0.77	27	empty
2	125	0.45	0.78	33	SO4
3	97	0.37	0.75	21	MG

Modifications

Observed in the structure: 7 modified (engineered).

Compared structures

4E6E · Crystal structure of a putative cell division protein FtsZ (Tfu_1113) from Thermobifida… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q47QW6
Elsewhere: RCSB PDB 4E6E · PDBe 4E6E · UniProt Q47QW6

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