MolNFT v1 · #89953 · protein

JAK1 kinase (JH1 domain) in complex with compound 30

4E4L: “JAK1 kinase (JH1 domain) in complex with compound 30”. X-ray diffraction. MolNFT v1 #89953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4E4L
Type: protein
Length: 1,125 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P23458

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	279	—	P23458
B	—	protein	281	—	P23458
E	—	protein	282	—	P23458
D	—	protein	283	—	P23458

Compared structures

4E4L · JAK1 kinase (JH1 domain) in complex with compound 30 · the same entry in another collection · chain D against D, TM-score 1.00
P23458 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase JAK1 (P23458) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23458
Elsewhere: RCSB PDB 4E4L · PDBe 4E4L · UniProt P23458

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