MolNFT v1 · #89801 · protein

Structure of parf-ADP form 2

4E03 · Plasmid partitioning protein parf: “Structure of parf-ADP form 2”. X-ray diffraction, 2 ligands (ADP, MG), 5 pockets (best druggability 0.47). MolNFT v1 #89801 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4E03
Type: protein
Length: 410 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plasmid partitioning protein parf
UniProt: B0ZE06
Ligands: ADP, MG
Pockets: 5 · best druggability 0.47

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plasmid partitioning protein parf	protein	204	50% helix, 17% strand	B0ZE06
B	Plasmid partitioning protein parf	protein	206	42% helix, 16% strand	B0ZE06

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	160	0.47	0.77	27	ADP, MG
2	130	0.45	0.77	24	ADP, MG
3	132	0.44	0.76	19	empty
4	52	0.31	0.77	17	empty
5	61	0.30	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 864 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

4E03 · Structure of ParF-ADP form 2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B0ZE06
Elsewhere: RCSB PDB 4E03 · PDBe 4E03 · UniProt B0ZE06

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