MolNFT v1 · #8950 · protein

Endopolygalacturonase from the phytopathogenic fungus fusarium moniliforme

1HG8: “Endopolygalacturonase from the phytopathogenic fungus fusarium moniliforme”. X-ray diffraction, 1 ligand (NAG), 1 pocket (best druggability 0.45). MolNFT v1 #8950 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1HG8
Type: protein
Length: 349 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endopolygalacturonase
UniProt: Q07181
Ligands: NAG
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endopolygalacturonase	protein	349	5% helix, 53% strand	Q07181

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	210	0.45	0.74	31	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1HG8 · Endopolygalacturonase from the phytopathogenic fungus Fusarium moniliforme · the same entry in another collection · chain A against A, TM-score 1.00
Q07181 · AlphaFold monomer V2.0 prediction for polygalacturonase (Q07181) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07181
Elsewhere: RCSB PDB 1HG8 · PDBe 1HG8 · UniProt Q07181

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