MolNFT v1 · #89464 · protein

Crystal structure of human HRASLS2

4DPZ · HRAS-like suppressor 2: “Crystal structure of human HRASLS2”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #89464 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4DPZ
Type: protein
Length: 109 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HRAS-like suppressor 2
EC: 2.3.1.-, 3.1.1.-
UniProt: Q9NWW9
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	HRAS-like suppressor 2 (EC 2.3.1.-, 3.1.1.-)	protein	109	25% helix, 29% strand	Q9NWW9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.33	0.75	16	empty

Modifications

Observed in the structure: 1 modified (oxidation).

Compared structures

4DPZ · Crystal structure of human HRASLS2 · the same entry in another collection · chain X against X, TM-score 1.00
Q9NWW9 · AlphaFold monomer V2.0 prediction for phospholipase a and acyltransferase 2 (Q9NWW9) · a predicted model of the same protein · chain X against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NWW9
Elsewhere: RCSB PDB 4DPZ · PDBe 4DPZ · UniProt Q9NWW9

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