MolNFT v1 · #89237 · protein

Crystal structure of the coiled-coil 1 domain of actin-binding protein SCAB1

4DJG · Plectin-related protein: “Crystal structure of the coiled-coil 1 domain of actin-binding protein SCAB1”. X-ray diffraction, 1 pocket (best druggability 0.44). MolNFT v1 #89237 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 4DJG
Type: protein
Length: 96 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Plectin-related protein
UniProt: O48791
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Plectin-related protein	protein	49	73% helix, 0% strand	O48791
B	Plectin-related protein	protein	47	81% helix, 0% strand	O48791

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.44	0.83	12	empty

Interfaces

1 interface between chains.

A–B · 950 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

4DJG · Crystal structure of the coiled-coil 1 domain of actin-binding protein SCAB1 · the same entry in another collection · chain A against A, TM-score 1.00
O48791 · AlphaFold monomer V2.0 prediction for stomatal closure-related actin- binding protein 1… · a predicted model of the same protein · chain B against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O48791
Elsewhere: RCSB PDB 4DJG · PDBe 4DJG · UniProt O48791

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