MolNFT v1 · #89168 · protein
Crystal structure of isoprenoid synthase A3MSH1 (target efi-501992) from pyrobaculum calidifontis
4DHD · Polyprenyl synthetase: “Crystal structure of isoprenoid synthase A3MSH1 (target efi-501992) from pyrobaculum calidifontis”. X-ray diffraction, 2 ligands (PO4, CL), 2 pockets (best druggability 0.67). MolNFT v1 #89168 on GenesisL1…
- PDB
- 4DHD
- Type
- protein
- Length
- 328 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polyprenyl synthetase
- UniProt
- A3MSH1
- Ligands
- PO4, CL
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 75% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polyprenyl synthetase | protein | 328 | 75% helix, 2% strand | A3MSH1 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
- CL · Chloride ion · ion · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 489 | 0.67 | 0.79 | 49 | PO4 |
| 2 | 79 | 0.42 | 0.79 | 14 | ACT |
Compared structures
- 4DHD · Crystal structure of isoprenoid synthase A3MSH1 (TARGET EFI-501992) from Pyrobaculum… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3MSH1
- Elsewhere: RCSB PDB 4DHD · PDBe 4DHD · UniProt A3MSH1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.