MolNFT v1 · #88889 · protein
Crystal structure of the ankyrin-B ZU5-ZU5-upa-dd tandem
4D8O · Ankyrin-2: “Crystal structure of the ankyrin-B ZU5-ZU5-upa-dd tandem”. X-ray diffraction, 9 pockets (best druggability 0.70). MolNFT v1 #88889 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4D8O
- Type
- protein
- Length
- 509 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ankyrin-2
- UniProt
- Q01484
- Pockets
- 9 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ankyrin-2 | protein | 509 | 19% helix, 39% strand | Q01484 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.70 | 0.90 | 21 | empty |
| 2 | 222 | 0.56 | 0.79 | 32 | empty |
| 3 | 169 | 0.50 | 0.77 | 27 | empty |
| 4 | 53 | 0.48 | 0.86 | 17 | empty |
| 5 | 208 | 0.47 | 0.74 | 23 | empty |
Compared structures
- 4D8O · Crystal Structure of the ankyrin-B ZU5-ZU5-UPA-DD tandem · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01484
- Elsewhere: RCSB PDB 4D8O · PDBe 4D8O · UniProt Q01484
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