MolNFT v1 · #88887 · protein

Crystal structure of bacillus thuringiensis CRY5B nematocidal toxin

4D8M · Pesticidal crystal protein CRY5BA: “Crystal structure of bacillus thuringiensis CRY5B nematocidal toxin”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #88887 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 4D8M
Type: protein
Length: 585 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pesticidal crystal protein CRY5BA
UniProt: Q45712
Pockets: 4 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pesticidal crystal protein CRY5BA	protein	585	31% helix, 30% strand	Q45712

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	93	0.53	0.84	16	empty
2	139	0.45	0.77	29	empty
3	115	0.38	0.74	18	empty
4	75	0.34	0.76	16	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

4D8M · Crystal structure of Bacillus thuringiensis Cry5B nematocidal toxin · the same entry in another collection · chain A against A, TM-score 1.00
Q45712 · AlphaFold monomer V2.0 prediction for pesticidal crystal protein CRY5BA (Q45712) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q45712
Elsewhere: RCSB PDB 4D8M · PDBe 4D8M · UniProt Q45712

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.