MolNFT v1 · #88830 · protein
Structural, biophysical and biochemical analyses of a clostridium perfringens sortase D5 transpeptidase
4D70 · Sortase family protein: “Structural, biophysical and biochemical analyses of a clostridium perfringens sortase D5 transpeptidase”. X-ray diffraction, 7 pockets (best druggability 0.53). MolNFT v1 #88830 on GenesisL1: 3D structure…
- PDB
- 4D70
- Type
- protein
- Length
- 320 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sortase family protein
- EC
- 3.4.22.70
- UniProt
- Q0TUL5
- Pockets
- 7 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Sortase family protein (EC 3.4.22.70) | protein | 160 | 26% helix, 39% strand | Q0TUL5 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.53 | 0.82 | 21 | empty |
| 2 | 128 | 0.51 | 0.80 | 21 | empty |
| 3 | 78 | 0.37 | 0.77 | 19 | empty |
| 4 | 107 | 0.35 | 0.73 | 30 | empty |
| 5 | 95 | 0.33 | 0.74 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 407 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 4D70 · Structural, biophysical and biochemical analyses of a Clostridium perfringens Sortase D5… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0TUL5
- Elsewhere: RCSB PDB 4D70 · PDBe 4D70 · UniProt Q0TUL5
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