MolNFT v1 · #88796 · protein

Structure of N-terminally truncated A49 from vaccinia virus western reserve

4D5T · Protein A49R: “Structure of N-terminally truncated A49 from vaccinia virus western reserve”. X-ray diffraction, 1 ligand (SO4), 11 pockets (best druggability 0.68). MolNFT v1 #88796 on GenesisL1: 3D structure, binding sites and…

PDB: 4D5T
Type: protein
Length: 1,204 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein A49R
UniProt: P31037
Ligands: SO4
Pockets: 11 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, D, E	Protein A49R	protein	151	77% helix, 0% strand	P31037
C, F, G, H	Protein A49R	protein	150	78% helix, 0% strand	P31037

Ligands and binding sites

SO4 · Sulfate ion · ion · 5 copies · chains A, C, D, F, G

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

11 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	394	0.68	0.80	44	empty
2	64	0.51	0.86	21	empty
3	132	0.48	0.78	24	empty
4	127	0.47	0.78	22	empty
5	131	0.47	0.77	24	empty

Interfaces

8 interfaces between chains.

C–G · 822 Å² buried · 5 hydrogen bonds · protein-protein
A–D · 821 Å² buried · 6 hydrogen bonds · protein-protein
A–H · 785 Å² buried · 6 hydrogen bonds · protein-protein
E–H · 606 Å² buried · 4 hydrogen bonds · protein-protein
A–F · 402 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

4D5T · Structure of N-terminally truncated A49 from Vaccinia Virus Western Reserve · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31037
Elsewhere: RCSB PDB 4D5T · PDBe 4D5T · UniProt P31037

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.