MolNFT v1 · #88782 · protein
Tetracycline repressor class H, apo form
4D5F · Tetracycline resistance repressor protein: “Tetracycline repressor class H, apo form”. X-ray diffraction, 2 ligands (SO4, CL), 2 pockets (best druggability 0.63). MolNFT v1 #88782 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4D5F
- Type
- protein
- Length
- 194 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetracycline resistance repressor protein
- UniProt
- Q9Z358
- Ligands
- SO4, CL
- Pockets
- 2 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetracycline resistance repressor protein | protein | 194 | 74% helix, 0% strand | Q9Z358 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
- CL · Chloride ion · ion · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 324 | 0.63 | 0.79 | 30 | empty |
| 2 | 72 | 0.32 | 0.74 | 14 | empty |
Compared structures
- 4D5F · tetracycline repressor class H, apo form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z358
- Elsewhere: RCSB PDB 4D5F · PDBe 4D5F · UniProt Q9Z358
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