MolNFT v1 · #88363 · protein
Pih N-terminal domain
4CSE · PIH1 domain-containing protein 1: “Pih N-terminal domain”. X-ray diffraction. MolNFT v1 #88363 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4CSE
- Type
- protein
- Length
- 236 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PIH1 domain-containing protein 1; Telomere length regulation protein TEL2 homolog
- UniProt
- Q9CQJ2, Q9DC40
Structure
x-ray diffraction · 4 distinct chains · 24% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PIH1 domain-containing protein 1 | protein | 111 | 24% helix, 32% strand | Q9CQJ2 |
| B | PIH1 domain-containing protein 1 | protein | 112 | 23% helix, 29% strand | Q9CQJ2 |
| C | Telomere length regulation protein TEL2 homolog | protein | 9 | 33% helix, 0% strand | Q9DC40 |
| D | Telomere length regulation protein TEL2 homolog | protein | 4 | 0% helix, 0% strand | Q9DC40 |
Interfaces
3 interfaces between chains.
- A–C · 475 Ų buried · 11 hydrogen bonds · protein-protein
- B–D · 336 Ų buried · 17 hydrogen bonds · protein-protein
- A–B · 290 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 4CSE · PIH N-terminal domain · the same entry in another collection · chain D against D, TM-score 1.00
- Q9CQJ2 · AlphaFold monomer V2.0 prediction for PIH1 domain-containing protein 1 (Q9CQJ2) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q9DC40 · AlphaFold monomer V2.0 prediction for telomere length regulation protein TEL2 homolog… · a predicted model of the same protein · chain D against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9CQJ2
- Every structure of UniProt Q9DC40
- Elsewhere: RCSB PDB 4CSE · PDBe 4CSE · UniProt Q9CQJ2 · UniProt Q9DC40
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