MolNFT v1 · #8823 · protein

Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor

1HCD: “Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor”. Solution nmr, 1 pocket (best druggability 0.63). MolNFT v1 #8823 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1HCD
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hisactophilin
UniProt: P13231
Pockets: 1 · best druggability 0.63

Structure

solution nmr · 1 distinct chain · 3% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hisactophilin	protein	118	3% helix, 49% strand	P13231

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	202	0.63	0.83	46	empty

Compared structures

1HCD · Structure of hisactophilin is similar to interleukin-1 beta and fibroblast growth factor · the same entry in another collection · chain A against A, TM-score 1.00
P13231 · AlphaFold monomer V2.0 prediction for hisactophilin-1 (P13231) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13231
Elsewhere: RCSB PDB 1HCD · PDBe 1HCD · UniProt P13231

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