MolNFT v1 · #8811 · protein
Solution NMR structure of the dimerization domain of the yeast transcriptional activator GAL4 (residues 50-106)
1HBW · Regulatory protein GAL4: “Solution NMR structure of the dimerization domain of the yeast transcriptional activator GAL4 (residues…”. Solution nmr, 2 pockets (best druggability 0.49). MolNFT v1 #8811 on GenesisL1: 3D structure…
- PDB
- 1HBW
- Type
- protein
- Length
- 114 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein GAL4
- UniProt
- P04386
- Pockets
- 2 · best druggability 0.49
Structure
solution nmr · 1 distinct chain · 49% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Regulatory protein GAL4 | protein | 57 | 49% helix, 0% strand | P04386 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 150 | 0.49 | 0.78 | 15 | empty |
| 2 | 131 | 0.44 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1245 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1HBW · Solution nmr structure of the dimerization domain of the yeast transcriptional activator… · the same entry in another collection · chain A against A, TM-score 1.00
- P04386 · AlphaFold monomer V2.0 prediction for regulatory protein GAL4 (P04386) · a predicted model of the same protein · chain B against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04386
- Elsewhere: RCSB PDB 1HBW · PDBe 1HBW · UniProt P04386
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