MolNFT v1 · #88052 · protein
Structure of crenactin, an archeal actin-like protein
4CJ7 · ACTIN/ACTIN family protein: “Structure of crenactin, an archeal actin-like protein”. X-ray diffraction, 1 ligand (ADP), 6 pockets (best druggability 0.83). MolNFT v1 #88052 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 4CJ7
- Type
- protein
- Length
- 852 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ACTIN/ACTIN family protein
- UniProt
- A3MWN5
- Ligands
- ADP
- Pockets
- 6 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ACTIN/ACTIN family protein | protein | 426 | 38% helix, 20% strand | A3MWN5 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1006 | 0.83 | 0.84 | 115 | ADP |
| 2 | 695 | 0.74 | 0.80 | 78 | ADP |
| 3 | 59 | 0.66 | 0.94 | 15 | empty |
| 4 | 112 | 0.41 | 0.76 | 19 | empty |
| 5 | 56 | 0.27 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1168 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A3MWN5
- Elsewhere: RCSB PDB 4CJ7 · PDBe 4CJ7 · UniProt A3MWN5
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