MolNFT v1 · #87967 · protein
Structure of regulator protein SCO3201 from streptomyces coelicolor
4CGR · Putative tetr-family transcriptional regulator: “Structure of regulator protein SCO3201 from streptomyces coelicolor”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.83). MolNFT v1 #87967 on GenesisL1: 3D…
- PDB
- 4CGR
- Type
- protein
- Length
- 388 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative tetr-family transcriptional regulator
- UniProt
- Q9KYU4
- Ligands
- PO4
- Pockets
- 2 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 79% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative tetr-family transcriptional regulator | protein | 197 | 78% helix, 0% strand | Q9KYU4 |
| B | Putative tetr-family transcriptional regulator | protein | 191 | 80% helix, 0% strand | Q9KYU4 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 977 | 0.83 | 0.84 | 94 | empty |
| 2 | 241 | 0.64 | 0.82 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 996 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 4CGR · Structure of Regulator Protein SCO3201 from Streptomyces coelicolor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9KYU4
- Elsewhere: RCSB PDB 4CGR · PDBe 4CGR · UniProt Q9KYU4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.