MolNFT v1 · #87891 · protein
Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2
4CEK · Regulator of nonsense transcripts 2: “Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2”. X-ray diffraction, 2 pockets (best druggability 0.45). MolNFT v1 #87891 on GenesisL1: 3D structure…
- PDB
- 4CEK
- Type
- protein
- Length
- 240 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulator of nonsense transcripts 2
- UniProt
- Q9HAU5
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of nonsense transcripts 2 | protein | 240 | 77% helix, 0% strand | Q9HAU5 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 175 | 0.45 | 0.75 | 27 | empty |
| 2 | 67 | 0.36 | 0.77 | 18 | empty |
Compared structures
- 4CEK · Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HAU5 · AlphaFold monomer V2.0 prediction for regulator of nonsense transcripts 2 (Q9HAU5) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HAU5
- Elsewhere: RCSB PDB 4CEK · PDBe 4CEK · UniProt Q9HAU5
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