MolNFT v1 · #87308 · protein

P4 protein from bacteriophage PHI8 (R32)

4BWY: “P4 protein from bacteriophage PHI8 (R32)”. X-ray diffraction, 20 pockets (best druggability 0.76). MolNFT v1 #87308 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4BWY
Type: protein
Length: 3,432 residues
Chains: 12
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: P4
UniProt: Q9MC14
Pockets: 20 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, F, G, H, I, J, K, L	P4	protein	288	32% helix, 29% strand	Q9MC14
E	P4	protein	264	32% helix, 30% strand	Q9MC14

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1024	0.76	0.79	98	empty
2	167	0.67	0.87	36	empty
3	138	0.67	0.88	33	empty
4	468	0.66	0.78	39	empty
5	154	0.66	0.87	35	empty

Interfaces

16 interfaces between chains.

G–I · 1678 Å² buried · 22 hydrogen bonds · protein-protein
A–C · 1672 Å² buried · 21 hydrogen bonds · protein-protein
H–I · 1669 Å² buried · 20 hydrogen bonds · protein-protein
B–C · 1660 Å² buried · 20 hydrogen bonds · protein-protein
B–D · 1656 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

4BWY · P4 protein from bacteriophage PHI8 (R32) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9MC14
Elsewhere: RCSB PDB 4BWY · PDBe 4BWY · UniProt Q9MC14

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