MolNFT v1 · #87260 · protein

Structure of Y190E mutant of PHAZ7 phb depolymerase

4BVK · Phb depolymerase PHAZ7: “Structure of Y190E mutant of PHAZ7 phb depolymerase”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #87260 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4BVK
Type: protein
Length: 685 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phb depolymerase PHAZ7
EC: 3.1.1.75
UniProt: Q939Q9
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 27% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phb depolymerase PHAZ7 (EC 3.1.1.75)	protein	341	28% helix, 17% strand	Q939Q9
B	Phb depolymerase PHAZ7 (EC 3.1.1.75)	protein	344	27% helix, 17% strand	Q939Q9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	136	0.41	0.75	28	empty

Interfaces

1 interface between chains.

A–B · 271 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 disulfide (disulfide).

Compared structures

4BVK · Structure of Y190E mutant of PhaZ7 PHB depolymerase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q939Q9
Elsewhere: RCSB PDB 4BVK · PDBe 4BVK · UniProt Q939Q9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.