MolNFT v1 · #87059 · protein
Mcl-1 bound to alpha beta puma BH3 peptide 2
4BPI · Fusion protein consisting of induced myeloid leukemia cell…: “Mcl-1 bound to alpha beta puma BH3 peptide 2”. X-ray diffraction, 1 ligand (CD). MolNFT v1 #87059 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4BPI
- Type
- protein
- Length
- 160 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion protein consisting of induced myeloid leukemia cell differentiation protein mcl-1…
- UniProt
- P97287, Q07820
- Ligands
- CD
Structure
x-ray diffraction · 2 distinct chains · 79% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion protein consisting of induced myeloid leukemia cell differentiation protein mcl-1 homolog | protein | 141 | 78% helix, 0% strand | P97287, Q07820 |
| B | Alpha beta BH3PEPTIDE | protein | 19 | 89% helix, 0% strand | — |
Ligands and binding sites
- CD · Cadmium ion · metal · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 875 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (nonstandard).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P97287
- Every structure of UniProt Q07820
- Elsewhere: RCSB PDB 4BPI · PDBe 4BPI · UniProt P97287 · UniProt Q07820
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