MolNFT v1 · #86842 · protein
Homology model of coxsackievirus A7 (CAV7) empty capsid proteins.
4BIQ · VP1: “Homology model of coxsackievirus A7 (CAV7) empty capsid proteins.”. Electron microscopy, 8 pockets (best druggability 0.77). MolNFT v1 #86842 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4BIQ
- Type
- protein
- Length
- 660 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- VP1; VP2; VP3
- UniProt
- I1T312, I1T315, I1T318
- Pockets
- 8 · best druggability 0.77
Structure
electron microscopy · 3 distinct chains · 13% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | VP1 | protein | 204 | 12% helix, 28% strand | I1T312 |
| B | VP2 | protein | 254 | 11% helix, 26% strand | I1T315 |
| C | VP3 | protein | 202 | 16% helix, 36% strand | I1T318 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 996 | 0.77 | 0.80 | 123 | empty |
| 2 | 1107 | 0.73 | 0.77 | 119 | empty |
| 3 | 750 | 0.67 | 0.76 | 109 | empty |
| 4 | 512 | 0.67 | 0.79 | 107 | empty |
| 5 | 224 | 0.46 | 0.74 | 36 | empty |
Interfaces
3 interfaces between chains.
- A–B · 382 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 298 Ų buried · 0 hydrogen bonds · protein-protein
- A–C · 172 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4BIQ · Homology model of coxsackievirus A7 (CAV7) empty capsid proteins. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I1T312
- Every structure of UniProt I1T315
- Every structure of UniProt I1T318
- Elsewhere: RCSB PDB 4BIQ · PDBe 4BIQ · UniProt I1T312 · UniProt I1T315 · UniProt I1T318
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