MolNFT v1 · #86806 · protein

A structural model of cap mutant (T127L and S128I) in cgmp- bound state

4BHP · Camp receptor protein: “A structural model of cap mutant (T127L and S128I) in cgmp- bound state”. Solution nmr, 1 pocket (best druggability 0.62). MolNFT v1 #86806 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4BHP
Type: protein
Length: 209 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Camp receptor protein
UniProt: P0ACJ8
Pockets: 1 · best druggability 0.62

Structure

solution nmr · 1 distinct chain · 30% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Camp receptor protein	protein	209	30% helix, 24% strand	P0ACJ8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.62	0.90	18	empty

Compared structures

4BHP · A structural model of CAP mutant (T127L and S128I) in cGMP-bound state · the same entry in another collection · chain A against A, TM-score 1.00
P0ACJ8 · AlphaFold monomer V2.0 prediction for camp-activated global transcriptional regulator crp… · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0ACJ8
Elsewhere: RCSB PDB 4BHP · PDBe 4BHP · UniProt P0ACJ8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.