MolNFT v1 · #86700 · protein
Solution structure of human ribosomal protein P1.P2 heterodimer
4BEH · 60S acidic ribosomal protein P1: “Solution structure of human ribosomal protein P1.P2 heterodimer”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #86700 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4BEH
- Type
- protein
- Length
- 230 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 60S acidic ribosomal protein P1; 60S acidic ribosomal protein P2
- UniProt
- P05386, P05387
- Pockets
- 1 · best druggability 0.33
Structure
solution nmr · 2 distinct chains · 32% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 60S acidic ribosomal protein P1 | protein | 114 | 32% helix, 0% strand | P05386 |
| B | 60S acidic ribosomal protein P2 | protein | 116 | 32% helix, 4% strand | P05387 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.33 | 0.77 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1361 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 4BEH · Solution structure of human ribosomal protein P1.P2 heterodimer · the same entry in another collection · chain A against A, TM-score 1.00
- P05386 · AlphaFold monomer V2.0 prediction for 60S acidic ribosomal protein P1 (P05386) · a predicted model of the same protein · chain A against A, TM-score 0.44
- P05387 · AlphaFold monomer V2.0 prediction for 60S acidic ribosomal protein P2 (P05387) · a predicted model of the same protein · chain B against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05386
- Every structure of UniProt P05387
- Elsewhere: RCSB PDB 4BEH · PDBe 4BEH · UniProt P05386 · UniProt P05387
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