MolNFT v1 · #86568 · protein
Mycobacterium tuberculosis chorismate synthase after exposure to 266NM UV laser
4BAJ: “Mycobacterium tuberculosis chorismate synthase after exposure to 266NM UV laser”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #86568 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4BAJ
- Type
- protein
- Length
- 375 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chorismate synthase
- EC
- 4.2.3.5
- UniProt
- P63611
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chorismate synthase (EC 4.2.3.5) | protein | 375 | 39% helix, 20% strand | P63611 |
Ligands and binding sites
- ACT · Acetate ion · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.56 | 0.76 | 34 | empty |
| 2 | 134 | 0.45 | 0.77 | 23 | empty |
| 3 | 50 | 0.26 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 4BAJ · MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE after exposure to 266nm UV laser · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63611
- Elsewhere: RCSB PDB 4BAJ · PDBe 4BAJ · UniProt P63611
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